Fraenkel, Liana;
Bathon, Joan;
England, Bryant;
St Clair, William;
Arayssi, Thurayya;
Carandang, Kristine;
Deane, Kevin;
Genovese, Mark;
Huston, Kent;
Kerr, Gail;
Akl, Elie;
Turner, Amy.
To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluat...
Lindner, Andreas K;
Lejon, Veerle;
Chappuis, François;
Seixas, Jorge;
Kazumba, Leon;
Barrett, Michael P;
Mwamba, Erick;
Erphas, Olema;
Akl, Elie A;
Villanueva, Gemma;
Bergman, Hanna;
Simarro, Pere;
Ebeja, Augustin Kadima;
Priotto, Gerardo;
Franco, Jose Ramon.
Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a parasitic infection that usually progresses to coma and death unless treated. WHO has updated its guidelines for the treatment of this infection on the basis of independent literature reviews and using the Grading of Recommendation...
Chou, Stella T;
Alsawas, Mouaz;
Fasano, Ross M;
Field, Joshua J;
Hendrickson, Jeanne E;
Howard, Jo;
Kameka, Michelle;
Kwiatkowski, Janet L;
Pirenne, France;
Shi, Patricia A;
Stowell, Sean R;
Thein, Swee Lay;
Westhoff, Connie M;
Wong, Trisha E;
Akl, Elie A.
Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and management of alloimmunization, delayed hemolytic transfusio...
